Nitrogen monoxide inhibits haem synthesis in mouse reticulocytes
نویسندگان
چکیده
منابع مشابه
Nitrogen monoxide inhibits haem synthesis in mouse reticulocytes.
AI (anaemia of inflammation) often manifests in patients with chronic immune activation due to cancer, chronic infections, autoimmune disorders, rheumatoid arthritis and other diseases. The pathogenesis of AI is complex and involves cytokine-mediated inhibition of erythropoiesis, insufficient erythropoietin production and diminished sensitivity of erythroid progenitors to this hormone, and rete...
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متن کاملGeminate carbon monoxide rebinding to a c-type haem.
A chemically modified form of cytochrome c(cyt. c), termed carboxymethyl cytochrome c(cm cyt. c), possesses a vacant sixth coordination site to the haem iron that is available to bind external ligands. We present data on the rapid flash photolysis of CO from the ferrous haem iron of cm cyt. c and describe the kinetics and spectral transitions that accompany the recombination. This was achieved ...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 2014
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj4620603